RESEARCH OVERVIEW
The most devastating aspect of a cancer diagnosis is the emergence of metastatic disease, which signifies that cancer cells have spread from the primary tumor to distant sites in the body. Once cancer has spread, the disease is largely incurable. Research pursued in my laboratory focuses on defining the molecular and cellular processes that facilitate cancer metastasis. These include tumor cell intrinsic processes such a cancer cell migration and invasion. Our research also investigates how cancer cells influence and respond to distinct microenvironments in the primary tumor as well as distant metastatic sites. Thus, our research program is dedicated towards the identification of clinically relevant, functional mediators of cancer metastasis. It is anticipated that these candidates will represent attractive targets for the development of therapeutic agents for improved management of metastatic cancers.
AFFILIATIONS & SUPPORT
Contact info
Rosalind and Morris Goodman Cancer Research Centre - McGill University
1160 Pine Ave. West (Room 508)
Montreal, Quebec (Canada)
H3A 1A3
T. 514.398.4259 (Siegel - Office)
T. 514.398.8889 (Siegel - Laboratory)
F. 514.398.6769 (Siegel - Fax)
peter.siegel@mcgill.ca
© 2011 Siegel Lab